What is Alpha-1 Antitrypsin Deficiency?
Alpha-1 Antitrypsin Deficiency also known as Alpha-1, A1AD or AATD is an inherited, genetic condition that is passed on from generation to generation. As the name suggests it is a deficiency of alpha-1 antitrypsin (AAT) in the bloodstream. AAT is an enzyme produced in the liver to help protect the tissues of the body during infections. The low level of AAT in the blood occurs because the AAT is abnormal and cannot be released from the liver at the normal rate. This leads to a build up of abnormal AAT in the liver that can cause liver disease and a decrease of AAT in the blood that can lead to lung disease.
Latest news
- Posted July 14, 2023
Coronavirus (COVID-19) 11th August 2022
It seems like a very long time since the alpha-1 community was facing the uncertain prospect of the COVID-19 pandemic […] - Posted July 14, 2023
What is happening with clinical trials in the UK as we slowly emerge from COVID-19, and how can you continue to support clinical research into new treatment options?
The last year has seen intense focus on the development of treatments and vaccines for COVID-19, along with respiratory clinicians […] - Posted July 14, 2023
European Pathways of Care in AATD Study
Patients : Please share this study with your clinicians and encourage them to participate. Identifying the different pathways of care […] - Posted July 14, 2023
Annual Meeting Update 2020
Annual Social Gathering & Information Day 2020 As many of our veteran members will know we have held our annual […]