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Alpha-1 Antitrypsin Deficiency also known as Alpha-1, A1AD or AATD is an inherited, genetic condition that is passed on from generation to generation. As the name suggests it is a deficiency of alpha-1 antitrypsin (AAT) in the bloodstream. AAT is an enzyme produced in the liver to help protect the tissues of the body during infections. The low level of AAT in the blood occurs because the AAT is abnormal and cannot be released from the liver at the normal rate. This leads to a build up of abnormal AAT in the liver that can cause liver disease and a decrease of AAT in the blood that can lead to lung disease.
Clinical utility of alpha-1 proteinase inhibitor...
Clinical utility of alpha-1 proteinase inhibitor in the management of adult patients with sever [ ... ]
New Report!
Our Trustee, Dr Sandra Nestler-Parr is a co author on this report published on 14th July 2017
Patient-Reported Outcome and Observer-Repo [ ... ]
EU ALPHA-1 AWARENESS DAY | 25 APRIL 2018
For the first time in history, the European Alpha-1 Community celebrates an EU Alpha-1 Awarene [ ... ]
PARTY IN THE PARK CHILDREN'S DAY
Saturday 19th August 2017
Folly Farm, Kilgetty, Wales
The Alpha-1 UK Support Group are holding our 2nd Party in [ ... ]
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