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Alpha-1 Antitrypsin Deficiency also known as Alpha-1, A1AD or AATD is an inherited, genetic condition that is passed on from generation to generation. As the name suggests it is a deficiency of alpha-1 antitrypsin (AAT) in the bloodstream. AAT is an enzyme produced in the liver to help protect the tissues of the body during infections. The low level of AAT in the blood occurs because the AAT is abnormal and cannot be released from the liver at the normal rate. This leads to a build up of abnormal AAT in the liver that can cause liver disease and a decrease of AAT in the blood that can lead to lung disease.
Linda Cooke
30th October 1950 – 21st January 2016
Our dear Linda Cooke sadly passed away peacefully with her son Andrew, daughter Helen and her best [ ... ]
This open letter is intended to give an update on the recent activities of the Alpha-1 UK Support Group on behalf of the Alpha-1 community in the UK, [ ... ]
Read MoreDear Alpha-1 Patients, We have repeatedly noticed that there still appears to exist confusion about the status of ADAPT and the available options for [ ... ]
Read MoreFurther to our announcement in April of the establishment of a multidisciplinary specialist NHS clinics for Alpha-1 patients in the West Midlands, we [ ... ]
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